When are platelets just platelets?

are platelets count useful for detecting the grade of steatosis?

The source of HLA molecules on platelets: Does platelets adsorb soluble HLA molecules from their environment?

Background: The origin and function of human leukocyte antigen (HLA) class I molecules on platelets are still highly arguable. Given the differences in the results of the previous studies in this regard, the lack of research in recent years, and the clinical importance of HLA class I molecules, the absorption capacity of platelets for soluble HLA class I molecules was studied in this investigat...

Procoagulant Platelets: Not Just Full of Hot Air Running title: Battinelli; Procoagulant Platelets: Not just full of hot air

Procoagulant platelets: are they necrotic?

Apoptosis and necrosis represent distinct cell death processes that regulate mammalian development, physiology and disease. Apoptosis characteristically leads to the silent destruction and removal of cells in the absence of an inflammatory response. In contrast, necrotic cell death can induce physiologic inflammatory responses linked to tissue defense and repair. Although anucleate, platelets u...

Platelets of female mice are intrinsically more sensitive to agonists than are platelets of males.

OBJECTIVE It has been reported that women fare worse after ischemic coronary events, but the mechanisms remain unclear. Because platelets play a central role in the formation of occlusive thrombi at sites of ruptured atherosclerotic plaques, we studied male/female paired mouse littermates for sex differences in platelet function. METHODS AND RESULTS We compared platelet reactivity in male/fem...